A New Theory for Ménière’s Disease

Ménière’s disease is an inner ear disorder characterized by vertigo attacks, fluctuating and progressive hearing loss, tinnitus, and aural fullness in the affected ear | Otolaryngology–Head and Neck Surgery

The pathophysiology of Ménière’s disease remains elusive. Theories so far are anatomical variation in the size or position of the endolymphatic sac and duct, viral inflammation or autoimmune involvement of the sac, or a genetically determined abnormality of endolymph control. Animal studies on blocking the ductus reuniens and endolymphatic duct have produced hydrops in the cochlea, saccule, and utricle. Cone beam computed tomography images show a similar pattern with apparent obstruction of the ductus reuniens, saccular duct, and endolymphatic sinus. New studies documenting the age of onset of Ménière’s disease show a pattern similar to benign paroxysmal positional vertigo, raising the possibility that the fundamental cause of Ménière’s disease might be detached saccular otoconia.

Full reference: Hornibrook, J. & Bird, P. (2017) A New Theory for Ménière’s Disease: Detached Saccular Otoconia. Otolaryngology-Head and Neck Surgery. Vol. 156 (Issue 2) pp. 350 – 352



Meniere’s, migraine, and motion sickness

Golding, J.F. & Patel, M. (2017) Acta Oto-Laryngologica. 137(5) pp. 492-502


Objectives: Pathologies of the vestibular system influence MSS. Bilateral vestibular deficits lower MSS, vestibular neuritis or benign paroxysmal positional vertigo have little overall effect, whereas vestibular migraine elevates MSS. However, less is known about MSS in MD, a condition in which many patients experience vestibular loss and migraine symptoms.

Conclusion: Elevated Motion Sickness Susceptibility (MSS) in Meniere’s disease (MD) is likely to be a consequence of the onset of MD and not migraine per se.

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Internet-based peer support for Ménière’s disease

Pyykkő, I. et al. International Journal of Audiology. Published online: 9 February 2017


Objective: This paper presents a summary of web-based data collection, impact evaluation, and user evaluations of an Internet-based peer support program for Ménière’s disease (MD).

Conclusions: We suggest that a web-based data collection and impact evaluation for peer support can be helpful while formulating the rehabilitation goals of building the self-confidence needed for coping and increasing social participation.

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Triple semicircular canal plugging: a novel modality for the treatment of intractable Meniere’s disease

Zhang, D. et al. (2016) Acta Oto-Laryngologica. 136(12) pp. 1230- 1235

Objective: To explore the long-term efficacy of triple semicircular canal plugging (TSCP) in the treatment of intractable Meniere’s disease (MD).

Conclusions: TSCP, which can reduce vertiginous symptoms in patients with intractable MD, represents an effective therapy for this disorder.

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Endolymphatic hydrops in patients with unilateral and bilateral Meniere’s disease

Morimoto, K. et al. (2017) Acta Oto-Laryngologica. 137(1) pp. 23-25

Objective: To evaluate the EH on both sides in patients with unilateral and bilateral MD, and to investigate factors with progression to bilateral MD including the degree of EH, hearing level, and the duration of MD.

Conclusion: All definite Meniere’s disease (MD) had endolymphatic hydrops (EH) at least in the cochlea or the vestibule. Symptoms of MD may appear after formation of EH. It is assumed that the probability of immediate progression to bilateral MD from unilateral MD is very low in patients without EH on the non-affected side.

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Positive experiences associated with acquired hearing loss, Ménière’s disease, and tinnitus: A review

Manchaiah, V et al. Positive experiences associated with acquired hearing loss, Ménière’s disease, and tinnitus: A review. International Journal of Audiology January 2015, Vol. 54, No. 1 , Pages 1-10

Objective: It is common to study and understand how various illness and disorders result in negative consequences. However, positive experiences have been reported in a range of disabling conditions including multiple sclerosis, heart disease, physical and sensory disabilities. This paper presents a literature review of studies that have explored positive experiences associated with acquired hearing loss, Ménière’s disease, and tinnitus.

Design: A review of the peer reviewed scientific literature. Study sample: A comprehensive search strategy identified 15 articles after applying inclusion criteria.

Results: A range of positive experiences have been reported by patients with hearing and balance disorders and by their significant others. Associations between demographic variables (e.g. age, gender), audiological variables (e.g. severity of the condition, duration) and the reported positive experiences are low. In Ménière’s disease, self-reported positive experiences can predict the impact of the condition. However, this phenomenon has not yet been demonstrated in relation to hearing loss and tinnitus.

Conclusions: Positive experiences associated with audio-vestibular disorders have been demonstrated. Further research is needed on the long-term benefits of the encouragement of such experiences and positive attitudes in persons with hearing loss, tinnitus, and imbalance